Gallic acid

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Gallic acid (3,4,5-trihydroxy benzoic acid) is an organic compounds and polyphenolic compounds. It is a powdery in the forms of organic crystals, sharp crystals or square crystals and it is colorless or pale yellow. It’s freely soluble in water, acetone, DMSO, methanol, alcohol, but it’s insoluble in benzene and chloroform and does not combine with protein. It is found throughout in plants such as raspberry, strawberry, blueberry, etc.

Gallic acid prepared from decomposition of gallotanin that is a precursor in the tannins synthesis of plants by ellagitannin.

Identity
3,4,5-trihydroxy benzoic acid
– Trade name : Gallic acid
– Molecular formula : (HO) 3C6H2CO2H
– Molecular Weight : 170.12 (1.7 g / cm3)
– Water solubility : 1.1 g / 100 ml. At 20 ° C
– Melting point : 250 °C (523 K)
– Boiling point : 258-265 °C (531-538 K)
– CAS Number : 149-91-7

• 3,4,5-Trihydroxybenzoic Acid Monohydrate
– Trade name : Gallic acid
– Molecular formula : (HO)3C6H2CO2H.H2O
– Molecular Weight : 188.13
– CAS Number : 5995-86-8

gallic acid

 

gallic acid fomular

Manufacture
• Degradation by microbes and extraction from tannin

Use and applications
• Substance used in manufacture of ink and ink photo
• Substance used in manufacture of esters such as propyl gallate and piro galloids, etc
• A component of drugs such as trimethoprim (TMP) with sulfonamides for antibacterial
• A leather tanning and finishing
• A chemical additive to food colors and food flavor in the food industry and beverage industry
• A component of dyes

Pharmaceutical activity
• Anti-fungal and antivirus
• Anti-inflammatory
• Anti-mutagenic
• Anti-cancer
• Anti-inflammatory
• Anti-oxidation and prevent cell
• Reduce of acid in stomach
• Prevent to the flow of blood to the colon and treatment of albumin high conditions in stomach
• Treatment of diabetes

Action of gallic acid for antioxidation and anticancer caused cells protection from damage of oxidation process in cells and cells protection from cytotoxicity of cancer, without harming healthy cells.

Gallic acid used for an astringent of internal haemorrhage with drinking or injecting and used to treat diabetes. Some ointment products that mix of gallic acid to treat psoriasis and external haemorrhoids. In addition, it is also used for a component of dyes and inks.